Normal aging and chronic UV exposure eventually result in problematic skin degeneration. Such degeneration is characterized by specific changes in skin composition – or, more specifically, changes in the dermal extra cellular matrix (ECM). Because of these changes, your skin may experience increased skin fragility, wrinkles, or a leathery appearance.

In a 60-person study, SYN®-COLL was compared against a placebo formula. Both products were used at recommended levels according to their active ingredients. Over 84 days, volunteers applied the serum twice a day.

Using the PRIMOS® technique, parallel stripe patterns are projected on the sample with successive phase shift. The analysis of fringe deformations provided a qualitative, as well as quantitative, evaluation of each height profile.

This molecule works by encouraging collagen synthesis in your fibroblasts

Collagen makes up a large part of the ECM’s dermal connective tissue. The multifunctional protein Thrombospondin I (TSP) activates the latent – but biologically inactive – form of Tissue Growth Factor (TGF).  We know that TGF is the key factor in collagen synthesis. It binds to a specific sequence in the TSP molecule, a sequence known as ARG-PHE-LYS.

SYN®-COLL can activate TGF, making it the perfect aqueous-based peptide for the job.  Its unique sequence is engineered to mimic your body’s own collagen-producing TGF procedure. By boosting collagen production,  SYN®-COLL yields firm, youthful skin.

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