Normal aging and chronic UV exposure eventually result in problematic skin degeneration. Such degeneration is characterized by specific changes in skin composition – or, more specifically, changes in the dermal extra cellular matrix (ECM). Because of these changes, your skin may experience increased skin fragility, wrinkles, or a leathery appearance.
In a 60-person study, SYN®-COLL was compared against a placebo formula. Both products were used at recommended levels according to their active ingredients. Over 84 days, volunteers applied the serum twice a day.
After 84 days of applying 2.5% SYN®-COLL twice a day, the Rz formula showed considerable effects. Put plainly, SYN®-COLL was found to have significant wrinkle-reducing and skin-smoothing effects.
This molecule works by encouraging collagen synthesis in your fibroblasts
Collagen makes up a large part of the ECM’s dermal connective tissue. The multifunctional protein Thrombospondin I (TSP) activates the latent – but biologically inactive – form of Tissue Growth Factor (TGF). We know that TGF is the key factor in collagen synthesis. It binds to a specific sequence in the TSP molecule, a sequence known as ARG-PHE-LYS.
SYN®-COLL can activate TGF, making it the perfect aqueous-based peptide for the job. Its unique sequence is engineered to mimic your body’s own collagen-producing TGF procedure. By boosting collagen production, SYN®-COLL yields firm, youthful skin.